For optimal control of flea and tick infestations, Simparica should be administered at monthly intervals and continued throughout the flea and/or tick season based on local epidemiological situations.

Simparica tablets are chewable and palatable and readily consumed by dogs when offered by the owner. If the tablet is not taken up voluntarily by the dog it can also be given with food or directly into the mouth. The tablets should not be divided.

Please follow dosage instructions provided by your vet. The table below may be used as reference:

Bodyweight (kg)

Tablet strength

(mg sarolaner)

Number of tablets to be administered

1.3 - 2.5



>2.5 - 5



>5 - 10



>10 - 20



>20 - 40



>40 - 60




Appropriate combination of tablets


Do not use in cases of hypersensitivity to the active substance or to any of the excipients.


Parasites need to start feeding on the host to become exposed to sarolaner; therefore, the transmission of infectious parasite-borne diseases cannot be excluded.


In the absence of available data, treatment of puppies less than 8 weeks of age and/or dogs less than 1.3 kg bodyweight should be based on a benefit-risk assessment by the responsible veterinarian.


The safety of Simparica has not been established during pregnancy and lactation or in animals intended for breeding.

Sarolaner is well tolerated in Collies with a deficient multidrug-resistance-protein 1 (MDR1 -/-) following single oral administration at 5 times the recommended dose. No treatment-related clinical signs were observed.

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SKU: simparica5mg
Simparica Palatable Tablets